Photoredox Radical\nTruce–Smiles Rearrangement\nof <i>N-</i>Sulfinyl Acrylamides with Bromodifluoroacetamides

We herein report a photochemical\nTruce–Smiles\nrearrangement\nreaction of <i>N</i>-sulfinyl acrylamides with bromodifluoroacetamides\nresulting in the synthesis of a series of aryl difluoroglutaramides\nin moderate to good yields. The asymmetric synthesis using chiral\nsulfinamides produced quaternary carbon<i>-</i>centered\nglutaramide products with a modest enantioselectivity. This protocol\neffectively complements previous Truce–Smiles rearrangement\nmethods involving <i>N</i>-sulfonyl acrylamides.