Photoredox/CopperDual-Catalyzed Three-Component PerfluoroalkylTrifluoromethylthiolation of Alkenes
A new three-component 1,2-perfluoroalkyl trifluoromethylthiolation of alkenes via dual photoredox/copper catalysis has been established, affording a variety of C<sub><i>n</i></sub>F<sub>2<i>n</i>+1</sub>/CF<sub>3</sub>S-containing molecules under mild conditions in a redox-neutral manner. This protocol exhibits excellent functional group tolerance, broad compatibility with various alkenes and perfluoroalkyl iodides, and potential utility in the modification of bioactive molecules.
Publication Details
- Journal
- Figshare
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1021/acs.orglett.5c00289.s001
- Primary Topic
- Mycorrhizal Fungi and Plant Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00