Transamination of\nZwitterionic\nQuinones with Polyamines:\nThe Carbon Bridge Matters

The\none-pot transamination reactions on a zwitterionic benzoquinonemonoimine\nyield either a quinoxaline derivative or bis-zwitterionic macrocycles,\ndepending on the number of carbon atoms bridging primary polyamines.\nThese latter products, featuring two confined donor cavities, are\nthe result of a [2 + 2] condensation without the need for template\neffect or high dilution conditions.