Regioselective Synthesisof β,γ-UnsaturatedAmides from Unactivated Alkenes

β,γ-Unsaturated amides are valuable substrates for downstream functionalization reactions but can be challenging to prepare. Herein, we introduce an approach featuring the regioselective addition of carbamoyl chlorides to unactivated alkenes, present its scope and limitations, and exemplify its synthetic utility.

Publication Details

Journal
Figshare
Published
2025-03-08
DOI
https://doi.org/10.1021/acs.joc.5c00093.s001
Primary Topic
Mycorrhizal Fungi and Plant Interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Regioselective Synthesisof β,γ-UnsaturatedAmides from Unactivated Alkenes

Figshare
Mycorrhizal Fungi and Plant Interactions
article

Regioselective Synthesisof β,γ-UnsaturatedAmides from Unactivated Alkenes

article en

Abstract

β,γ-Unsaturated amides are valuable substrates for downstream functionalization reactions but can be challenging to prepare. Herein, we introduce an approach featuring the regioselective addition of carbamoyl chlorides to unactivated alkenes, present its scope and limitations, and exemplify its synthetic utility.

Figshare
Openalex Percentile: Top 57%
Mycorrhizal Fungi and Plant Interactions
DOISourceOpenAlex
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Regioselective Synthesisof β,γ-UnsaturatedAmides from Unactivated Alkenes · Figshare (2025) | TGRS Research Map | TGRS