Supplementary material for the manuscript <b>Clinical course of COVID-19 in children with Adrenal Insufficiency: Results from National Data</b><b>.</b>

There has been concern about a potential increase in the incidence or severity of Coronavirus Disease 2019 (COVID-19) in individuals with adrenal insufficiency (AI). Data on the course of SARS-CoV-2 infection in AI children are lacking. Objective of the study is to evaluate whether children with AI are more susceptible to the infection or are at risk of severe COVID-19.1143 children with AI have been included. Of these, 148 patients, 112 with primary (PAI) and 36 with secondary AI (SAI), and 74 control subjects with normal adrenal function, who contracted SARS-CoV-2, were evaluated for the severity and outcomes of infection.Our findings do not indicate that AI is associated with increased susceptibility to SARS-CoV-2 infection or higher risk for severe COVID-19 in children.