Adverse association between ketosis and ovarian activity in Canadian dairy cows: Supplementary data

Ketosis is a major metabolic disease characterized by high concentration of ketone bodies including β-hydroxy butyrate (BHB) in dairy cows. Although we and others have demonstrated the negative relationship between ketosis and reproductive performance of lactating cows, the mechanisms are not clear. We investigated the association between ketosis, determined by milk BHB concentrations during 3-14 days in milk (DIM), and ovarian activity, measured by milk progesterone (P4) profiles within 150 DIM in Holstein cows.