Four new phenylpropanoid glycosides from the leaves of <i>Illicium dunnianum</i> and their neuroprotective activities

Four previously unreported phenylpropanoid glycosides (<b>1</b>–<b>4</b>), together with four known analogues (<b>5</b>–<b>8</b>), were isolated from the leaves of <i>Illicium dunnianum</i>. The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in H<sub>2</sub>O<sub>2</sub>-induced OLN-93 cell injury model.

Publication Details

Journal
Figshare
Published
2024-08-15
DOI
https://doi.org/10.6084/m9.figshare.26748696
Primary Topic
Magnolia and Illicium research
Type
article
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Four new phenylpropanoid glycosides from the leaves of Illicium dunnianum and their neuroprotective activities

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Magnolia and Illicium research
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Four new phenylpropanoid glycosides from the leaves of Illicium dunnianum and their neuroprotective activities

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Abstract

Four previously unreported phenylpropanoid glycosides (<b>1</b>–<b>4</b>), together with four known analogues (<b>5</b>–<b>8</b>), were isolated from the leaves of <i>Illicium dunnianum</i>. The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in H<sub>2</sub>O<sub>2</sub>-induced OLN-93 cell injury model.

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Magnolia and Illicium research
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Four new phenylpropanoid glycosides from the leaves of <i>Illicium dunnianum</i> and their neuroprotective activities · Figshare (2024) | TGRS Research Map | TGRS