A Study on Incidence of Dengue and Efficacy of Caripill a Papaya Extract in Mild and Moderate Cases in a Tertiary Care Hospital

Dengue is a mosquito borne viral infection with major complication thrombocytopenia. According to WHO, high incidence of dengue over 6.5 million cases with more than 7300 dengue related deaths were reported in 2023. This study aimed to assess the incidence of dengue and effect of Caripill, a papaya leaf extract in augmented clinical outcomes in moderately affected dengue patients in a tertiary care center. A prospective observational study conducted from May 2023 to april 2024 in Durgabai Deshmukh Hospital & Research Center, Vidyanagar Hyderabad. A total of seventy-five Patients enrolled were treated with Caripill and followed up daily for 5 days with monitoring platelet and other hematological parameters. Total subjects were evaluated for efficacy and safety. All the subjects significantly increased their platelet count from 80,800 on Day 1 to 116,093 on Day 5; (P = 0.0001) and improved hemoglobin levels, RBC levels, and systolic blood pressure. Symptoms were typical of dengue with fever, myalgia, and dyspnea being most prevalent. Caripill significantly increased the platelet count and selective hematologic improvements that could make it an adjunct therapy for dengue.