Formulation and Evaluation of Herbal Effervescent Tablet

The study aims to obtain the best formulation for the production of effervescent tablets made from ginger as well as to determine their physicochemical characteristics. In present work an attempt has been made to formulate an effervescent tablet containing immediate release Gingerol using various acids and base. The effervescent tablets were prepared by wet granulation technique. Lactose as a binder and talc as lubricant were used. There are three formulations that content the citric acid and sodium bicarbonate were formulated. These three formulations were evaluated for the flow ability of granules was evaluated, including flow rate, angle of repose, bulk density, tapped density, Carr's index, Hausner ratio, and effervescent time. The physical stability of granules such as organoleptic evaluation, effervescent time, and pH measurement was also evaluated after 28 d of storage. From above study it was concluded that F3 shows the better result than the F1 & F2.