Evaluation of Analgesic & Anti-Inflammatory Effect of Hydroalcoholic Extract Obtained from Leaves of Asparagus racemosus on Experimental Model

Asparagus racemosus Linn is a member of the Liliaceae family. This species contains various chemical constituents that contribute to its therapeutic properties. The present research focuses on evaluating the analgesic and anti-inflammatory effects of a hydroalcoholic extract derived from the leaves of Asparagus racemosus. To achieve this, the hydroalcoholic extract of the chosen plant was utilized to assess both analgesic and anti-inflammatory activities. In the present study, diclofenac sodium (10mg/kg, p.o.) was utilized as a reference medication. The hydroalcoholic leaf extract (200 and 400mg/kg, p.o.) of Asparagus racemosus was evaluated for its analgesic and anti-inflammatory effects on Wistar albino rats. The findings of this research indicated that HEAR (200 and 400mg/kg, p.o.) exhibited significant (P<0.05) analgesic and anti-inflammatory properties in a dose-dependent fashion. Moreover, HEAR (200 and 400mg/kg, p.o.) demonstrated efficacy comparable to that of the standard drug, diclofenac sodium (10mg/kg, p.o.). All experimental procedures were conducted under stringent supervision and with appropriate care of the animals, having received approval from the Institutional Animal Ethics Committee (IAEC). It was concluded that the HEAR was effective in a dose dependent manner and possessed potent analgesic and anti-inflammatory activities.