Cervical Catheter in Addition To Prostaglandin for Induction of Labour in Second Trimester IUFD

Abstract Aim: This study is to assess the efficacy of transcervical catheter with misoprostol, as compared to misoprostol alone for termination of pregnancy after a fetal death in second trimester. Method: This is a single center, non-randomized, prospective study which included, women requiring interruption in pregnancy either after fetal death or in a fetus with lethal anomalies between 14 to 28 weeks of gestation. The participants were non randomly allocated to groups with induction by misoprostol (400ug every 6 hourly vaginally) alone or added with transcervical catheter. This study attempts to synthesize the existing evidence for the use of cervical catheter in addition with misoprostol. Results: The outcomes measured out of the study are time duration to delivery, clinical chorioamnionitis (raised maternal temperature and tachycardia) and any other adverse outcomes. The composite evidence suggests that a regimen combining cervical catheter and misoprostol shortens the time to expulsion, though the overall success rates are similar to those seen with misoprostol only regimen but it did result in occurrence of clinical chorioamnionitis.