Effectiveness of long-lasting insecticidal nets for malaria elimination in Laos (2016-2023)

Introduction. Malaria remains a significant health challenge in Laos, particularly in the southern provinces with dense forests and mobile populations. Despite progress in reducing cases, socio-environmental factors drive its persistence. Materials and Methods. Using data from 2016 to 2023, trends were analysed with P-trend analysis, and effects of long-lasting insecticidal nets (LLIN) and climate on malaria incidence were assessed via Poisson regression. Results. During this period, malaria incidence decreased by 95.5%, underscoring the success of elimination strategies. LLIN distribution led to a 54.1% reduction in incidence (IRR=0.459; p 0.002). Climate factors did not significantly influence transmission rates (IRR=0.67; p 0.717). Conclusions. The critical role of LLINs in reducing malaria incidence is evident. To support the national elimination goal for 2030, interventions must maintain consistent coverage and community engagement. Future research should focus on localised climatic data and address specific challenges in regions like Khammouane Province, enhancing the effectiveness of malaria control programmes and improving intervention strategies.