Development and Assessment of Naturally Derived Tamarind Kernel Powder as Disintegrant in Beta-Blocker Atenolol Tablet

One common cardiovascular condition that needs to be effectively managed is hypertension. A beta-blocker called atenolol is frequently used to treat hypertension. Using tamarind seed kernel powder (TSKP) as a natural disintegrant, the study sought to create and assess atenolol tablets. TSKP was used in the formulation of the tablets, and their physical properties, dissolves profile, and disintegration time were assessed. The tablets quick and total dissolving, as demonstrated by the results, suggested that TSKP might be used as a natural disintegrant. By demonstrating the feasibility of using Tamarind seed kernel powder is a naturally occurring disintegrant in atenolol tablets, this work offers a feasible approach for the creation of naturally derived excipient-based hypertension therapy drugs.