UV-VIS Spectrophotometric Method for Estimating Furosemide in Dosage Form

This study reports the development of a UV-Vis spectrophotometric method for the estimation of furosemide in pharmaceutical dosage forms using water as the solvent. The furosemide showed maximum absorption at wavelength 277 nm and exhibited linearity over the concentration range of 5–25 µg/ml, with a correlation coefficient (R²) of 0.999. Precision studies showed an RSD of 0.123%, and accuracy recovery between 98-101%. The assay of a marketed furosemide tablet detected 98.86% of the label claim. Overall, the developed method is simple, sensitive, and reproducible, making it well suited for routine pharmaceutical analysis.