Study of Liver Development in Laboratory Mice Embryos mus musculus

Abstract : The current study aimed to follow up some embryonic developments in the Swiss white mice Mus musculus to identify the nature of these developments in order to increase scientific knowledge from this aspect as well as the importance of mice as a model for experimental studies.The liver is the largest internal organ that provides essential metabolic and endocrine functions, these include the production of bile, metabolism of nutritional compounds, detoxification, regulation of glucose levels through glycogen storage and control of blood balance by secreting clotting factors and serum proteins.Hepatocytes are the main cell type in the liver, accounting for about 70% of adult organ mass, hepatocytes and biliary epithelial cells are derived from the embryonic endoderm while visceral cells, astrocytes, kupffer cells and vascular cells are of mesoderm origin.After the occurrence of internal fertilization, the fertilized egg begins to divide until the blastomeres divide into the trophectoderm, which forms the placenta in the future, and the mass of internal cells that later form the embryo.