Clinicopathological Study of Tumors and Tumor like Lesions of Nose, Paranasal Sinuses and Nasopharynx

Abstract Objective: To find out the incidence, age, sex, site-wise distribution and various histopathological pattern of sinonasal and nasopharyngeal tumors and tumor like lesions. Method: In three year study, from January 2014 to December 2016, total of 201 adequate biopsy are analysed. The biopsy samples are received in 10% buffered formalin, routinely processed for histopathological examination and section are stained by H & E stain. Special stain and IHC done whenever required. Result: Among 201 samples, 158 are non-neoplastic and 43 are neoplastic lesions. Most common age group affected is 21-50 years (54.23%). Mean age is 38.06+19.19 years. The males (67.66%) are most commonly affected as compared to females (32.34%). Male to female ratio found to be 2.09:1. Nasal cavity (37.31%) is the most common site followed by maxillary sinus (25.37%). Most of the sinonasal masses are unilateral (70.15%) and rest are bilateral (29.85%). Sinusitis (34.33%) and mass with rhinorrhoea (28.86%) is the most common presenting symptom. Non-neoplastic lesions constituted about 84.48% cases. Amongst them Inflammatory Polyp is the most common accounting for a total of 112 cases (70.89%) followed by Allergic Polyp 20 cases (12.66%). Neoplastic lesion constituted about 21.39% cases. Out of which 14 cases (32.56%) are benign and 29 cases (67.44%) are malignant. Amongst benign, inverted papilloma 7 cases (50.00%) and amongt the malignant squamous carcinoma 11 cases (37.93%). Conclusion: we concluded that Inflammatory polyp is the most common polypoidal lesion. Non neoplastic lesions are most common than neoplastic lesions. However, they share same clinical and radiological features, therefore require Histopathological confirmation.