Bilayer Tablets in Pharmaceutical Technology: An Insight into Innovation and Development

A new and improved pharmaceutical dosage form called a bilayer tablet was created to get around some of the drawbacks of traditional single-layer tablets. Because of their two separate layers, incompatible medications can be physically separated, and various release profiles, such immediate and sustained release, can be combined into a single device. By administering an initial loading dose and a maintenance dose, this dual-layer method improves therapeutic efficacy and is particularly helpful for disorders that call for both quick and sustained action. Bilayer tablets not only increase patient compliance but also provide versatility in creating fixed-dose combinations, allowing for sequential or synchronized medication administration. The method is especially useful for decreasing the frequency of doses and attaining regulated release. Bilayer tablets are a substantial improvement in drug distribution, with promise future uses in a variety of therapeutic areas, despite certain manufacturing and stability issues.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-08
DOI
https://doi.org/10.5281/zenodo.16777524
Primary Topic
Genome Rearrangement Algorithms
Type
article
Field-Weighted Citation Impact
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article

Bilayer Tablets in Pharmaceutical Technology: An Insight into Innovation and Development

Zenodo (CERN European Organization for Nuclear Research)
Genome Rearrangement Algorithms
article

Bilayer Tablets in Pharmaceutical Technology: An Insight into Innovation and Development

article en

Abstract

A new and improved pharmaceutical dosage form called a bilayer tablet was created to get around some of the drawbacks of traditional single-layer tablets. Because of their two separate layers, incompatible medications can be physically separated, and various release profiles, such immediate and sustained release, can be combined into a single device. By administering an initial loading dose and a maintenance dose, this dual-layer method improves therapeutic efficacy and is particularly helpful for disorders that call for both quick and sustained action. Bilayer tablets not only increase patient compliance but also provide versatility in creating fixed-dose combinations, allowing for sequential or synchronized medication administration. The method is especially useful for decreasing the frequency of doses and attaining regulated release. Bilayer tablets are a substantial improvement in drug distribution, with promise future uses in a variety of therapeutic areas, despite certain manufacturing and stability issues.

Zenodo (CERN European Organization for Nuclear Research)
Industry, innovation and infrastructure
Openalex Percentile: Top 49%
Genome Rearrangement Algorithms
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