CHO Cell Antibody Drug Production

Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the production due to their complex posttranslational modification capabilities.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-27
DOI
https://doi.org/10.5281/zenodo.14935799
Primary Topic
Statistical Methods and Applications
Type
article
Field-Weighted Citation Impact
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article

CHO Cell Antibody Drug Production

Zenodo (CERN European Organization for Nuclear Research)
Statistical Methods and Applications
article

CHO Cell Antibody Drug Production

article en

Abstract

Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the production due to their complex posttranslational modification capabilities.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 52%
Statistical Methods and Applications
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