Dapagliflozin Analysis: A Review on Chromatography and Spectroscopic Methods

Dapagliflozin is an anti-diabetic drug. Dapagliflozin comes under new class of SGLT-2 inhibitor. It is administered as tablets. This therapeutic agent used for type 2 diabetes mellitus. Dapagliflozin functions by inhibiting glucose reabsorption in the proximal tubules of the kidney's nephron, it efficiently lowers blood glucose levels and promotes glycosuria. In this review article we study about profile of Dapagliflozin which include mechanism of action, pharmacokinetics, pharmacodynamics, adverse effects and drug interactions. Also reported analytical methods including UV, HPLC and HPTLC for assessment of Dapagliflozin single form and Dapagliflozin with other drugs are reviewed in this article.