Zebrafish as a Pharmacological Model: A Comprehensive Review

AbstractZebra fish (Danio rerio) has emerged as a versatile and valuable model organism in pharmacology, toxicology, and drug development. Due to its genetic similarities to humans, rapid development, and the ability to perform high-throughput screenings, zebrafish has become an increasingly popular tool for understanding drug mechanisms, studying disease models, and evaluating therapeutic efficacy. This review highlights the key features of zebrafish that make them an attractive pharmacological model, their use in drug discovery, their advantages over traditional models, and the challenges faced in their application. Keywords: Zebra fish, Pharmacology, Genetic studies, Danio rerio, Toxicology Studies.