CLINICAL AND SURGICAL APPROACHES TO CHRONIC RHINOSINUSITIS IN ADULT PATIENTS

Chronic rhinosinusitis (CRS) is a multifactorial inflammatory disorder of the nasal and paranasal sinus mucosa persisting for more than 12 weeks. It significantly impairs patients’ quality of life through persistent nasal obstruction, facial pain, and olfactory dysfunction. The complexity of CRS arises from diverse etiologies, heterogeneous immunopathological mechanisms, and varied clinical presentations, complicating treatment strategies. This study retrospectively analyzes clinical presentations, diagnostic modalities, and treatment outcomes of medical and surgical management in adult patients with CRS. Emphasis is placed on differentiating CRS phenotypes—CRSwNP and CRSsNP—and optimizing individualized treatment. Functional endoscopic sinus surgery (FESS) remains a cornerstone for refractory cases, restoring sinus ventilation and drainage. The findings underscore the importance of integrated care combining medical and surgical approaches for improved patient outcomes.