Analysis of Sodium Bicarbonate Injection Ear Bath for Fungal Otitis Externa

Objective: This study aims to systematically evaluate the clinical efficacy of sodium bicarbonate injection ear bath in treating fungal otitis externa, providing scientific evidence and new strategies for managing this condition. Methods: A total of 80 patients diagnosed with fungal otitis externa in the Department of Otorhinolaryngology at our hospital between June 2021 and June 2024 were enrolled as research subjects and randomly divided into an observation group and a control group. The observation group received treatment with sodium bicarbonate injection ear bath, while the control group was treated with traditional antifungal drugs (local application of triamcinolone acetonide econazole cream). Detailed records were maintained for both groups regarding treatment outcomes, symptom/sign improvement times (e.g., ear itching relief time and secretion reduction time), adverse reaction occurrences, and fungal negativity rates. Results: Comparative analysis of the treatment effects between the two groups revealed that the observation group demonstrated significant advantages in multiple aspects. First, in terms of treatment effectiveness, the cure rate and marked improvement rate were significantly higher in the observation group than in the control group (P < 0.05). Second, regarding symptom relief speed, the disappearance time of ear itching was significantly shorter in the observation group compared to the control group (P < 0.05), and recovery time was also significantly shorter in the observation group (P < 0.05). Additionally, the incidence of adverse reactions was significantly lower in the observation group than in the control group (P < 0.05). Conclusion: Sodium bicarbonate injection ear bath represents an effective method for treating fungal otitis externa. By regulating the acid-base balance of the external auditory canal to inhibit fungal growth, it significantly enhances treatment effectiveness, shortens symptom improvement time, and features simple operation and high safety, making it worthy of further promotion and application in clinical practice.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-16
DOI
https://doi.org/10.5281/zenodo.15668862
Primary Topic
Marine and coastal plant biology
Type
article
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article

Analysis of Sodium Bicarbonate Injection Ear Bath for Fungal Otitis Externa

Zenodo (CERN European Organization for Nuclear Research)
Marine and coastal plant biology
article

Analysis of Sodium Bicarbonate Injection Ear Bath for Fungal Otitis Externa

article en

Abstract

Objective: This study aims to systematically evaluate the clinical efficacy of sodium bicarbonate injection ear bath in treating fungal otitis externa, providing scientific evidence and new strategies for managing this condition. Methods: A total of 80 patients diagnosed with fungal otitis externa in the Department of Otorhinolaryngology at our hospital between June 2021 and June 2024 were enrolled as research subjects and randomly divided into an observation group and a control group. The observation group received treatment with sodium bicarbonate injection ear bath, while the control group was treated with traditional antifungal drugs (local application of triamcinolone acetonide econazole cream). Detailed records were maintained for both groups regarding treatment outcomes, symptom/sign improvement times (e.g., ear itching relief time and secretion reduction time), adverse reaction occurrences, and fungal negativity rates. Results: Comparative analysis of the treatment effects between the two groups revealed that the observation group demonstrated significant advantages in multiple aspects. First, in terms of treatment effectiveness, the cure rate and marked improvement rate were significantly higher in the observation group than in the control group (P < 0.05). Second, regarding symptom relief speed, the disappearance time of ear itching was significantly shorter in the observation group compared to the control group (P < 0.05), and recovery time was also significantly shorter in the observation group (P < 0.05). Additionally, the incidence of adverse reactions was significantly lower in the observation group than in the control group (P < 0.05). Conclusion: Sodium bicarbonate injection ear bath represents an effective method for treating fungal otitis externa. By regulating the acid-base balance of the external auditory canal to inhibit fungal growth, it significantly enhances treatment effectiveness, shortens symptom improvement time, and features simple operation and high safety, making it worthy of further promotion and application in clinical practice.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 54%
Marine and coastal plant biology
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