A 48 Year Old Female with Quadriparesis Secondary to Sjögren's Syndrome with Atypical Presentation: A Case Report

Sjögren's Syndrome is a autoimmune disease which is characterized by lymphocytic infiltration of exocrine glands, resulting in symptoms related to impaired exocrine gland, particularly lacrimal and salivary gland function such as xerostomia, keratoconjunctivitis sicca and profound B-cell Hyperactivity. The syndrome has unique features since it presents with a wide clinical spectrum from organ specific to systemic disease. The aim of this paper is to present a case of Sjögren's Syndrome, with atypical presentation as Quadriparesis. A 48 year old Female presented with acute onset, progressive muscle weakness of two day duration. On detailed evaluation, she was found to have low Potassium levels, Positive ANA Profile, Positive Schirmer’s Test, Distal Renal Tubular Acidosis. In our case, the patient primarily presented with Quadriparesis due Hypokalemic Periodic Paralysis due to distal RTA. Patient incidentally also had other features of Sjogren’s Syndrome including Dry eyes (Positive Schirmer’s Test), Xerostomia, Positive Rheumatoid Factor.