A review on "Topical gels: an emerging drug delivery system"

Topical drug distribution is the application of a substance to the skin for the aim of treating or curing skin problems. Gels, creams, and ointments are the most often used semisolid formulations for topical medicine administration. Gels have been popular in cosmetics and topical medicinal treatments in recent years due to their advantageous properties such as being greaseless, easily spreadable, and quickly detachable. In compared to creams and ointments, gel formulations have greater application properties and stability. A gel is a network of cross-linked polymers that expand in a liquid media. Gels are homogenous, semisolid preparations that typically consist of one or more medicament solutions or dispersions in appropriate hydrophilic or hydrophobic bases. Clinical research suggests that topical gels are the safest and most effective treatment choice for skin-related disorders, and that they are used topically to lessen associated adverse effects when compared to other traditional dose forms. The purpose of this article is to discuss the concepts and recent advancements in topical gels, such as classification, techniques of manufacture, characteristics, evaluation factors, and applications.