THE PATHOMORPHOLOGICAL SIGNIFICANCE OF HLA-DR EXPRESSION IN CASES OF GESTATIONAL PYELONEPHRITIS AMONG PREGNANT WOMEN

Gestational pyelonephritis (GP) is one of the most common and high-risk infectious-inflammatory conditions encountered during pregnancy, posing a serious threat to both maternal and fetal health. Understanding the role of the immune system in such cases is crucial for comprehending the pathogenesis of the disease. From this perspective, assessing the expression of the HLA-DR molecule—a key component in antigen presentation—provides an opportunity to better understand the underlying pathomorphological mechanisms of gestational pyelonephritis.