Formulation and Evaluation of Syrup from Oroxylum Indicum Bark for Relieving Period Cramps (Primary Dysmenorrhea)

Dysmenorrhea, characterized by painful menstrual cramps, significantly impacts women's daily activities. Conventional treatments like NSAIDs offer relief but pose risks with long-term use. This study aimed to develop and evaluate a polyherbal syrup containing Oroxylum indicum bark extract, known for its analgesic, anti-inflammatory, and spasmolytic properties, as a natural remedy for dysmenorrhea. The formulation was assessed for physicochemical parameters and underwent in vitro and in vivo evaluations. Results showed significant pain-relieving, spasmolytic, and anti-inflammatory effects, along with favorable stability and high sensory acceptability. The findings support the syrup’s potential as a safe and effective natural alternative for dysmenorrhea management.