Seroprevalence and Knowledge of Hepatitis B and C among Healthcare workers in three healthcare centers in Nigeria

The study investigated the seroprevalence and knowledge of viral hepatitis B and C infections among healthcare workers in three medical centers in Karu Local Government area, Nasarawa State, Nigeria. A cross-sectional study design was used in this study and data was collected using quantitative method. Structured interviewer-administered questionnaires were administered to 215 healthcare workers who were tested for HBsAg and anti- HCV using rapid hepatitis screening kits (ACON Laboratories biotest rapid diagnostic strips, USA). Data was analyzed using Chi square test and the level of significance, alpha – α, was set at < 5%. The overall seroprevalence of hepatitis among the healthcare workers were HBsAg 13.0% and HCV 2.8%. Seroprevalence of HBsAg among the unskilled workers was the highest at 4.6 %. There was no significant association between HBsAg and HCV seroprevalence across all the cadres (p ≤ 0.05). Doctors demonstrated a good knowledge of HBsAg and HCV (88%) compared to unskilled workers with poor knowledge scoring (9%). Knowledge base among HCWs was insignificant (p < 0.05). Although, the skilled HCWs had the highest screening and vaccination uptake, there was no statistically significant association (p ≤ 0.05) between the HBsAg prevalence, screening and vaccination across all the cadres. This study revealed a significant level of seroprevalence of HBsAg and HCV among the HCWs and poor knowledge, and low screening and vaccine uptake among unskilled workers in the three medical centers.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-05
DOI
https://doi.org/10.5281/zenodo.16535741
Primary Topic
Vaccine Coverage and Hesitancy
Type
article
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article

Seroprevalence and Knowledge of Hepatitis B and C among Healthcare workers in three healthcare centers in Nigeria

Zenodo (CERN European Organization for Nuclear Research)
Vaccine Coverage and Hesitancy
article

Seroprevalence and Knowledge of Hepatitis B and C among Healthcare workers in three healthcare centers in Nigeria

article en

Abstract

The study investigated the seroprevalence and knowledge of viral hepatitis B and C infections among healthcare workers in three medical centers in Karu Local Government area, Nasarawa State, Nigeria. A cross-sectional study design was used in this study and data was collected using quantitative method. Structured interviewer-administered questionnaires were administered to 215 healthcare workers who were tested for HBsAg and anti- HCV using rapid hepatitis screening kits (ACON Laboratories biotest rapid diagnostic strips, USA). Data was analyzed using Chi square test and the level of significance, alpha – α, was set at < 5%. The overall seroprevalence of hepatitis among the healthcare workers were HBsAg 13.0% and HCV 2.8%. Seroprevalence of HBsAg among the unskilled workers was the highest at 4.6 %. There was no significant association between HBsAg and HCV seroprevalence across all the cadres (p ≤ 0.05). Doctors demonstrated a good knowledge of HBsAg and HCV (88%) compared to unskilled workers with poor knowledge scoring (9%). Knowledge base among HCWs was insignificant (p < 0.05). Although, the skilled HCWs had the highest screening and vaccination uptake, there was no statistically significant association (p ≤ 0.05) between the HBsAg prevalence, screening and vaccination across all the cadres. This study revealed a significant level of seroprevalence of HBsAg and HCV among the HCWs and poor knowledge, and low screening and vaccine uptake among unskilled workers in the three medical centers.

Zenodo (CERN European Organization for Nuclear Research)
Federal University Lafia (NG), National Institute for Pharmaceutical Research and Development (NG), National Institutes of Pharmaceutical Research and Development (China) (CN)
No poverty
Openalex Percentile: Top 45%
Vaccine Coverage and Hesitancy
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Seroprevalence and Knowledge of Hepatitis B and C among Healthcare workers in three healthcare centers in Nigeria · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS