The WorkflowHub: A FAIR Registry for computational workflows

Presentation from the eScience Lab (The University of Manchester) at the ISMB/ECCB 2025 conference (view all). WorkflowHub is presented in the BOSC track as a Poster: B-091, Tuesday 22 July, 10:00-11:20 and 16:00-16:40 (viewable Mon and Tue). Project Website: https://workflowhub.eu/, https://workflowhub.org Source Code: https://github.com/seek4science/seek/tree/workflow/ License: BSD 3-Clause License Main Text of Abstract WorkflowHub is a free, open-source registry built to support the sharing and discovery of computational workflows, standard operating procedures, and their associated research assets. It boosts collaboration and scientific transparency by making workflows easier to co-create, discover, cite, and share - helping research become more reproducible and aligned with FAIR (Findable, Accessible, Interoperable, Reusable) data principles. Supporting widely adopted standards such as the Common Workflow Language, RO-Crate, Bioschemas, FAIR Signposting, and GA4GH’s TRS API, WorkflowHub integrates smoothly with other platforms and tools. Its new RO-Crate submission API allows research communities to programmatically create and update workflow entries, streamlining catalogue maintenance. WorkflowHub connects with external services to enhance metadata. For example, it integrates with BBMRI-ERIC’s LifeMonitor to assess workflow health and availability. It can also be used to connect workflows with the software they depend upon, for instance the ELIXIR (Life Science community) tools catalogue: bio.tools.,The platform is agnostic of workflow submission language and format, and is intended to span research domains; it currently hosts over 817 workflows in 35 formats, with more than 300 teams contributing across disciplines like life sciences, health, chemistry, biodiversity, climate science, and astronomy. Users can register ‘draft’ workflows to co-develop through team collaboration, which may itself be cross-institutional. Finalised workflows can be assigned (free) DOIs, with versioning, enabling proper citation. WorkflowHub serves a truly international community, and is coordinated by ELIXIR in partnership with the Australian BioCommons. Its development is shaped by its users through regular community events, and through biweekly WorkflowHub Club calls.