A Review on Stimuli Responsive Drug Delivery Systems

The drug delivery systems which respond to the stimuli are the most advanced systems, helps in diagnosing the diseases and treating them. Different types of stimuli have unique mechanism of drug release, which provides the targeted and controlled release of drug. Different stimuli such as temperature, pH, enzymatic, light, ultrasound, magnetic, mechanical, electrical and redox stimuli help in the drug delivery at the targeted regions in the body. Especially used for cancer chemotherapy. Based on the environment around the diseased state the drug will get release, high temperature around the cancer cell leads to the drug release when the drug is incorporated in the temperature sensitive polymer. In the same way different polymers respond in different ways based on the stimuli. There are many applications of stimuli responsive drug delivery systems such as cancer chemotherapy, in the treatment of inflammatory diseases, arthritis, Alzheimer’s disease and cardiac diseases. Also had wide scope in tissue engineering.