Automated Blood Cell Classification Using Convolutional Neural Networks (CNN)

The accurate classification of blood cells from biomedical images is critical for diagnosinghematological disorders and advancing clinical research. This study presents a robust approachto automated blood cell classification using a Convolutional Neural Network (CNN) applied toa dataset of 5,000 images across five classes: basophil, erythroblast, monocyte, myeloblast, andsegmented neutrophil. The methodology integrates data augmentation techniques (random rotation, zoom, and flip) and a custom CNN architecture with convolutional, batch normalization,and dropout layers to enhance generalization and mitigate overfitting. The model was trainedon 4,000 images and validated on 1,000 images, achieving a validation accuracy of 96.0% anda loss of 0.127 after 21 epochs, with early stopping and learning rate reduction strategies optimizing performance. Evaluation via a normalized confusion matrix revealed high class-specificprecision, with diagonal values exceeding 0.89 for all categories. The trained model was savedfor future deployment, demonstrating potential for real-time blood cell analysis in medical diagnostics. This work highlights the efficacy of deep learning in processing biomedical images andits promise for improving diagnostic workflows.

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-15
DOI
https://doi.org/10.5281/zenodo.15030678
Primary Topic
Digital Imaging for Blood Diseases
Type
article
Field-Weighted Citation Impact
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article

Automated Blood Cell Classification Using Convolutional Neural Networks (CNN)

Zenodo (CERN European Organization for Nuclear Research)
Digital Imaging for Blood Diseases
article

Automated Blood Cell Classification Using Convolutional Neural Networks (CNN)

article en

Abstract

The accurate classification of blood cells from biomedical images is critical for diagnosinghematological disorders and advancing clinical research. This study presents a robust approachto automated blood cell classification using a Convolutional Neural Network (CNN) applied toa dataset of 5,000 images across five classes: basophil, erythroblast, monocyte, myeloblast, andsegmented neutrophil. The methodology integrates data augmentation techniques (random rotation, zoom, and flip) and a custom CNN architecture with convolutional, batch normalization,and dropout layers to enhance generalization and mitigate overfitting. The model was trainedon 4,000 images and validated on 1,000 images, achieving a validation accuracy of 96.0% anda loss of 0.127 after 21 epochs, with early stopping and learning rate reduction strategies optimizing performance. Evaluation via a normalized confusion matrix revealed high class-specificprecision, with diagonal values exceeding 0.89 for all categories. The trained model was savedfor future deployment, demonstrating potential for real-time blood cell analysis in medical diagnostics. This work highlights the efficacy of deep learning in processing biomedical images andits promise for improving diagnostic workflows.

Zenodo (CERN European Organization for Nuclear Research)
Indian Institute of Technology Guwahati (IN)
Openalex Percentile: Top 53%
Digital Imaging for Blood Diseases
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Automated Blood Cell Classification Using Convolutional Neural Networks (CNN) · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS