Subclinical Hypothyroidism Post-Bariatric Surgery: A Reversible Case of Iodine Deficiency Without Autoimmune Thyroid Disease

Abstract : Subclinical hypothyroidism is a common finding in clinical practice, often prompting initiation of levothyroxine therapy. However, not all cases of elevated thyroid-stimulating hormone (TSH) reflect permanent thyroid dysfunction. This report discusses a 39-year-old woman with a history of Roux-en-Y gastric bypass surgery who presented with elevated TSH in the absence of thyroid autoantibodies or classic hypothyroid symptoms. Laboratory and clinical findings suggested iodine deficiency as the underlying cause. Her TSH normalized following potassium iodide supplementation. This case underscores the need for a nuanced approach to managing elevated TSH, particularly in post-bariatric surgery patients where iodine deficiency may be the etiology of subclinical hypothyroidism.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-02
DOI
https://doi.org/10.5281/zenodo.15574190
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Subclinical Hypothyroidism Post-Bariatric Surgery: A Reversible Case of Iodine Deficiency Without Autoimmune Thyroid Disease

Zenodo (CERN European Organization for Nuclear Research)
Thyroid Disorders and Treatments
article

Subclinical Hypothyroidism Post-Bariatric Surgery: A Reversible Case of Iodine Deficiency Without Autoimmune Thyroid Disease

article en

Abstract

Abstract : Subclinical hypothyroidism is a common finding in clinical practice, often prompting initiation of levothyroxine therapy. However, not all cases of elevated thyroid-stimulating hormone (TSH) reflect permanent thyroid dysfunction. This report discusses a 39-year-old woman with a history of Roux-en-Y gastric bypass surgery who presented with elevated TSH in the absence of thyroid autoantibodies or classic hypothyroid symptoms. Laboratory and clinical findings suggested iodine deficiency as the underlying cause. Her TSH normalized following potassium iodide supplementation. This case underscores the need for a nuanced approach to managing elevated TSH, particularly in post-bariatric surgery patients where iodine deficiency may be the etiology of subclinical hypothyroidism.

Zenodo (CERN European Organization for Nuclear Research)
Norman Regional Hospital (US), Zaporizhzhia State Medical and Pharmaceutical University (UA), University of Nigeria Teaching Hospital (NG), University of Duhok (IQ)
Good health and well-being
Openalex Percentile: Top 43%
Thyroid Disorders and Treatments
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Subclinical Hypothyroidism Post-Bariatric Surgery: A Reversible Case of Iodine Deficiency Without Autoimmune Thyroid Disease · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS