Anthelmintic Activity of Hymenocallis Littoralis Leaves Extract on Indian Earthworm (Pheretima Posthuma)

The present study aimed to evaluate the anthelmintic activity of both aqueous and ethanolic extracts of Hymenocallis littoralis using Indian earthworms (Pheretima posthuma) as the test organisms. The findings demonstrated that all extracts exhibited anthelmintic properties in a dose-dependent manner. Notably, the effectiveness of each extract was inversely related to the time taken for the paralysis or death of the worms. The anthelmintic effects were found to be comparable to those of the standard reference drug, Albendazole. Among the two extracts, the ethanolic extract showed the most significant anthelmintic activity, surpassing both the aqueous extract and the standard drug. The ethanol extract of Hymenocallis Littorallis caused paralysis time for 50 mg/ml is 26.44 and death time is 157.27 and for 100 mg/ml the paralysis time is 18.61 min. and death time are 94.06 min. The reference drug Albendazole (10 mg/ml) showed the paralysis at 11.30 min and death time 34.15 min respectively. These results support the traditional use of Hymenocallis littoralis in folk medicine as a natural anthelmintic agent.