Microneedle Technology: Advancements, Applications, and Future Different Directions

Microneedle Technology: Progress, Uses, and Prospects Micro needles, micro meter-sized instruments for minimally invasive transdermal delivery, provide an auspicious option against conventional injections. This review canvasses the new developments in micro needle technology with features of pain-free application, better drug bioavailability, and minimizing bio hazardous waste. We consider here the several different types of microneedles, namely, solid, coated, dissolving, and hydrogel, specifically designed for selected drug delivery strategies and therapeutic indications. The manufacturing process, especially the creation of wax moulds, is described in detail, highlighting material choice and manufacturing processes important for accurate microneedle design. Applications of this technology range from pharmaceuticals to cosmetics and diagnostics, taking advantage of its capacity to penetrate the stratum corneum and trigger wound healing mechanisms. Challenges still exist in the form of dose constraints, possible inflammation, and intricate manufacturing processes. Future research directions involve biodegradable microneedles, biosensors integrated into the microneedles for real-time monitoring, and nanotechnology-based drug delivery. To address today's needs using multidisciplinary studies, it will unlock even more of microneedle's potential towards effective patient-friendly healthcare options.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-20
DOI
https://doi.org/10.5281/zenodo.15473290
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
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article

Microneedle Technology: Advancements, Applications, and Future Different Directions

Zenodo (CERN European Organization for Nuclear Research)
Advancements in Transdermal Drug Delivery
article

Microneedle Technology: Advancements, Applications, and Future Different Directions

article en

Abstract

Microneedle Technology: Progress, Uses, and Prospects Micro needles, micro meter-sized instruments for minimally invasive transdermal delivery, provide an auspicious option against conventional injections. This review canvasses the new developments in micro needle technology with features of pain-free application, better drug bioavailability, and minimizing bio hazardous waste. We consider here the several different types of microneedles, namely, solid, coated, dissolving, and hydrogel, specifically designed for selected drug delivery strategies and therapeutic indications. The manufacturing process, especially the creation of wax moulds, is described in detail, highlighting material choice and manufacturing processes important for accurate microneedle design. Applications of this technology range from pharmaceuticals to cosmetics and diagnostics, taking advantage of its capacity to penetrate the stratum corneum and trigger wound healing mechanisms. Challenges still exist in the form of dose constraints, possible inflammation, and intricate manufacturing processes. Future research directions involve biodegradable microneedles, biosensors integrated into the microneedles for real-time monitoring, and nanotechnology-based drug delivery. To address today's needs using multidisciplinary studies, it will unlock even more of microneedle's potential towards effective patient-friendly healthcare options.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 59%
Advancements in Transdermal Drug Delivery
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