Study On Efficacy and Compliance of Oral Supplements with Ferric Pyrophosphate and Ferrous Ascorbate in Iron Deficiency Anaemia During Pregnancy

Background: Iron deficiency anaemia in pregnancy is a nutritional disorder characterized by insufficient iron levels, leading to reduced haemoglobin production. This condition poses significant risks to both maternal and fatal health including increased chances of preterm birth, low birth, weight and maternal morbidity. It often results from inadequate dietary intake, poor iron absorption, or increased iron requirements during pregnancy. Early diagnosis and appropriate management through iron supplementation and dietary adjustments are crucial to mitigate adverse outcomes and promote healthy pregnancy outcomes. Objective: To evaluate the efficacy and compliance with oral ferric pyrophosphate and oral ferrous ascorbate Method: A prospective observational study for a duration of 3 months with 83 subjects divided into 2 groups Group-Awith 43 subjects receiving Ferric ascorbate and Group-B with 40 subjects receiving with ferric pyrophosphate. Both the groups received a dose of 100mg oral tablets. Result: Ferrous Ascorbate showed an increase of Hb levels from 9.52 g/dL to 12.23 g/dL Serum Ferritin increased from 74.56ng/mL to 288.23ng/mL whereas in Ferric Pyrophosphate the Hb levels resulted from 9.82g/dL to 11.16g/dL and Serum Ferritinvalues increased from 82.63ng/mL to 314. 18ng/mL. Conclusion: Efficacy of Ferrous Ascorbate group was found to be better, but the Ferric Pyrophosphate group had better compliance compared to FerrousAscorbate.