QUETIAPINE FUMARATE ANALYSIS: A REVIEW OF CURRENT AND EMERGING TECHNIQUES

Quetiapine fumarate, a dibenzothiazepine derivative, is classified as a second-generation antipsychotic drug used to treat schizophrenia. The current study primarily focusses on development of analytical and bioanalytical methods, along with several techniques established for the estimation of quetiapine fumarate, whether in bulk or pharmaceutical dose form. Although they enable us to use cutting-edge analytical equipment to acquire both qualitative and quantitative results, analytical methods are essential for determining compositions. The analytical method for quetiapine fumarate may be chromatographic, spectral or hyphenated. Understanding important process factors and reducing their impact on accuracy and precision are made easier with the help of these techniques. Development of analytical methods is necessary to maintain high standards for commercial product quality and to comply with legal obligations. The development of analytical techniques is essential to sustaining regulatory requirements and maintaining high standards for the quality of commercial products. Bioanalytical techniques are intended to quantify the concentration of drugs, metabolite, or usual biomarker present in different biological fluids, such as tissue extracts, urine, serum, and saliva.