Blood loss due to injuries in children and its effect on the cardiovascular system

Blood loss in children is one of the key causes of complications in traumatic injuries and requires a special approach in diagnosis and treatment. Due to the age-related anatomical and physiological features of the child's body, such as a smaller volume of circulating blood, a high metabolic rate and immaturity of compensatory mechanisms, even moderate blood loss can lead to severe hemodynamic disorders. The paper examines the pathophysiological changes in the cardiovascular system in acute blood loss in children, including a decrease in blood pressure, tachycardia, impaired organ perfusion and the development of hypovolemic shock. Special attention is paid to the critical temporal aspects of the diagnosis and implementation of infusion-transfusion therapy. The authors analyze modern approaches to the treatment of pediatric patients with an emphasis on the need for an individual approach. The principles of selection of infusion media, transfusion preparations and volumes, as well as the use of modern methods of hemodynamic monitoring are described. A special place is given to the prevention of hypoxia and multiple organ failure. The presented data emphasize the importance of early detection of blood loss and timely therapy to prevent severe complications and improve the prognosis in children.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-12
DOI
https://doi.org/10.5281/zenodo.14861199
Citations
1
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.81
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article

Blood loss due to injuries in children and its effect on the cardiovascular system

1 citations
Zenodo (CERN European Organization for Nuclear Research)
Epigenetics and DNA Methylation
0.81
article

Blood loss due to injuries in children and its effect on the cardiovascular system

article en
1 citations

Abstract

Blood loss in children is one of the key causes of complications in traumatic injuries and requires a special approach in diagnosis and treatment. Due to the age-related anatomical and physiological features of the child's body, such as a smaller volume of circulating blood, a high metabolic rate and immaturity of compensatory mechanisms, even moderate blood loss can lead to severe hemodynamic disorders. The paper examines the pathophysiological changes in the cardiovascular system in acute blood loss in children, including a decrease in blood pressure, tachycardia, impaired organ perfusion and the development of hypovolemic shock. Special attention is paid to the critical temporal aspects of the diagnosis and implementation of infusion-transfusion therapy. The authors analyze modern approaches to the treatment of pediatric patients with an emphasis on the need for an individual approach. The principles of selection of infusion media, transfusion preparations and volumes, as well as the use of modern methods of hemodynamic monitoring are described. A special place is given to the prevention of hypoxia and multiple organ failure. The presented data emphasize the importance of early detection of blood loss and timely therapy to prevent severe complications and improve the prognosis in children.

Zenodo (CERN European Organization for Nuclear Research)
Institute of Experimental Cardiology (RU), 17th City Children's Clinical Polyclinic (BY), Saratov State Medical University (RU), North Ossetian State Medical Academy (RU)
Good health and well-being
Openalex Percentile: Top 21%
Epigenetics and DNA Methylation
0.81
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Blood loss due to injuries in children and its effect on the cardiovascular system · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS