OTOSCLEROSIS: PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND ADVANCES IN TREATMENT

Otosclerosis is a pathological bone remodeling disorder affecting the middle and inner ear. The term derives from "oto," meaning ear, and "sclerosis," referring to abnormal hardening. Initially described by Antonio Maria Valsalva in 1735 and later characterized pathologically by Adam Politzer in 1839, otosclerosis involves the replacement of the normal dense endochondral bone of the otic capsule with irregular spongy bone, which eventually hardens and leads to fixation of the stapes footplate.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-19
DOI
https://doi.org/10.5281/zenodo.14890904
Primary Topic
Ear Surgery and Otitis Media
Type
article
Field-Weighted Citation Impact
0.00
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article

OTOSCLEROSIS: PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND ADVANCES IN TREATMENT

Zenodo (CERN European Organization for Nuclear Research)
Ear Surgery and Otitis Media
article

OTOSCLEROSIS: PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND ADVANCES IN TREATMENT

article en

Abstract

Otosclerosis is a pathological bone remodeling disorder affecting the middle and inner ear. The term derives from "oto," meaning ear, and "sclerosis," referring to abnormal hardening. Initially described by Antonio Maria Valsalva in 1735 and later characterized pathologically by Adam Politzer in 1839, otosclerosis involves the replacement of the normal dense endochondral bone of the otic capsule with irregular spongy bone, which eventually hardens and leads to fixation of the stapes footplate.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 39%
Ear Surgery and Otitis Media
DOIOpen Access PDFOpenAlex
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OTOSCLEROSIS: PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND ADVANCES IN TREATMENT · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS