A Review on Effervescent Granules

Effervescent granules are a type of medication that comes in the form of dry powder particles, containing one or more active ingredients, and sometimes additional substances. Effervescent granules are commonly used due to their low toxicity and quick action. These granules are coated and usually contain a medication, acid compounds, and carbonates or bicarbonates, which react with water to release carbon dioxide. This review offers a comprehensive understanding of the fundamental mechanisms of effervescent granules, along with their essential properties and excipients employed. It explores different approaches for formulating and assessing the product. Various methods can be employed to prepare effervescent granules, including the wet method, dry method, hot-melt extrusion, and non-aqueous methods.