From lab to landscape: How models predict gene drive spread

This article reviews the key modeling approaches used to simulate gene drive dynamics. It explores how models contribute to risk assessment, containment strategies, and policy development while also addressing their limitations and future directions. As gene drive research progresses, integrating ecological, epidemiological, and decision-support models will be essential for responsible innovation. As a living literature review, this article will be updated with new modeling insights and methodologies as they become available.