PLATELET COUNTS IN PREGNANT WOMEN WITH PREECLAMPSIA

Preeclampsia (PE) is a pregnancy-related complication leading to development of acute hypertensive condition that still continues to be a major concern for Obstetricians. Platelets play a key role in its pathogenesis since their activation leads to increased consumption and abnormal values, which can be used as markers of disease progression. Mean platelet volume (MPV) and platelet distribution width (PDW) are also the most important markers of platelet heterogeneity. Elevated MPV reflects the size of more active larger platelets, and elevated PDW reflects enhanced platelet heterogeneity, both of which have been linked to vascular function in preeclampsia. Although the platelet indices have been mentioned in the context of hypertensive disorders, there is still no finding of how they forecast severity and complications in PE.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-07
DOI
https://doi.org/10.5281/zenodo.14987019
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

PLATELET COUNTS IN PREGNANT WOMEN WITH PREECLAMPSIA

Zenodo (CERN European Organization for Nuclear Research)
Respiratory Support and Mechanisms
article

PLATELET COUNTS IN PREGNANT WOMEN WITH PREECLAMPSIA

article en

Abstract

Preeclampsia (PE) is a pregnancy-related complication leading to development of acute hypertensive condition that still continues to be a major concern for Obstetricians. Platelets play a key role in its pathogenesis since their activation leads to increased consumption and abnormal values, which can be used as markers of disease progression. Mean platelet volume (MPV) and platelet distribution width (PDW) are also the most important markers of platelet heterogeneity. Elevated MPV reflects the size of more active larger platelets, and elevated PDW reflects enhanced platelet heterogeneity, both of which have been linked to vascular function in preeclampsia. Although the platelet indices have been mentioned in the context of hypertensive disorders, there is still no finding of how they forecast severity and complications in PE.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 37%
Respiratory Support and Mechanisms
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