A REVIEW ON THE THERAPEUTIC POTENTIAL OF GENE THERAPY IN NEUROLOGICAL DISORDERS

Gene therapy is a novel way to treating neurological illnesses, potentially curing some of the most difficult and incurable conditions at this time. This review examines the therapeutic potential of gene therapy for a range of neurological illnesses, with an emphasis on the mechanisms underlying these effects, such as cell-based therapies, gene silencing, gene editing, gene insertion, and gene control. Gene therapy offers intriguing pathways to address the underlying causes of neurological illnesses by repairing genetic defects, lowering toxic protein levels, improving neuroprotection, restoring gene function, and offering long-term solutions. The review focuses on important developments in tailored treatment plans, gene delivery techniques, and ongoing research initiatives that are influencing the direction of gene therapy. A thorough discussion of the therapeutic effects of gene therapy is provided, with an emphasis on how it may change treatment paradigms and enhance patient outcomes for diseases like spinal muscular atrophy, Huntington's disease, ALS, Parkinson's disease, and other neurological disorders.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-08-14
DOI
https://doi.org/10.5281/zenodo.13320813
Primary Topic
Parallel Computing and Optimization Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

A REVIEW ON THE THERAPEUTIC POTENTIAL OF GENE THERAPY IN NEUROLOGICAL DISORDERS

Zenodo (CERN European Organization for Nuclear Research)
Parallel Computing and Optimization Techniques
article

A REVIEW ON THE THERAPEUTIC POTENTIAL OF GENE THERAPY IN NEUROLOGICAL DISORDERS

article en

Abstract

Gene therapy is a novel way to treating neurological illnesses, potentially curing some of the most difficult and incurable conditions at this time. This review examines the therapeutic potential of gene therapy for a range of neurological illnesses, with an emphasis on the mechanisms underlying these effects, such as cell-based therapies, gene silencing, gene editing, gene insertion, and gene control. Gene therapy offers intriguing pathways to address the underlying causes of neurological illnesses by repairing genetic defects, lowering toxic protein levels, improving neuroprotection, restoring gene function, and offering long-term solutions. The review focuses on important developments in tailored treatment plans, gene delivery techniques, and ongoing research initiatives that are influencing the direction of gene therapy. A thorough discussion of the therapeutic effects of gene therapy is provided, with an emphasis on how it may change treatment paradigms and enhance patient outcomes for diseases like spinal muscular atrophy, Huntington's disease, ALS, Parkinson's disease, and other neurological disorders.

Zenodo (CERN European Organization for Nuclear Research)
Guntur Medical College (IN)
Good health and well-being
Openalex Percentile: Top 56%
Parallel Computing and Optimization Techniques
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A REVIEW ON THE THERAPEUTIC POTENTIAL OF GENE THERAPY IN NEUROLOGICAL DISORDERS · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS