Non-Invasive Therapeutic Drug Monitoring: LC-MS Validation for Lamotrigine Quantification in Dried Blood Spot and Oral Fluid/Saliva

Figure S1 LC-MS separation of six antiepileptic drugs to examine the resolution which is evident from extracted ion chromatograms of predefined analytes. LEV-levetiracetam, LTG-lamotrigine, LCS-lacosamide, CNB-cenobamate, ESLI-eslicarbazepine, CBZ-carbamazepine. Analyte concentration was at the level of fourth concentration point in saliva.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-01
DOI
https://doi.org/10.5281/zenodo.15117965
Primary Topic
Plant Molecular Biology Research
Type
article
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article

Non-Invasive Therapeutic Drug Monitoring: LC-MS Validation for Lamotrigine Quantification in Dried Blood Spot and Oral Fluid/Saliva

Zenodo (CERN European Organization for Nuclear Research)
Plant Molecular Biology Research
article

Non-Invasive Therapeutic Drug Monitoring: LC-MS Validation for Lamotrigine Quantification in Dried Blood Spot and Oral Fluid/Saliva

article en

Abstract

Figure S1 LC-MS separation of six antiepileptic drugs to examine the resolution which is evident from extracted ion chromatograms of predefined analytes. LEV-levetiracetam, LTG-lamotrigine, LCS-lacosamide, CNB-cenobamate, ESLI-eslicarbazepine, CBZ-carbamazepine. Analyte concentration was at the level of fourth concentration point in saliva.

Zenodo (CERN European Organization for Nuclear Research)
Masaryk University (CZ), Central European Institute of Technology – Masaryk University (CZ)
Good health and well-being
Openalex Percentile: Top 67%
Plant Molecular Biology Research
DOIOpen Access PDFOpenAlex
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Non-Invasive Therapeutic Drug Monitoring: LC-MS Validation for Lamotrigine Quantification in Dried Blood Spot and Oral Fluid/Saliva · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS