Case Series on the Application of Plasma Rich Platelet

Objective: The objective of this case series is to evaluate the effectiveness of Platelet-Rich Plasma (PRP) therapy in treating various gynecological conditions, including cervical ectropion, recurrent candidiasis, and stress urinary incontinence (SUI). The aim is to determine the therapeutic benefits of PRP in cases where conventional treatments have proven insufficient or unsuitable. Methodology: This case series includes three patients treated with PRP therapy for different gynecological conditions. Blood was collected from each patient, and PRP was prepared using a two-step centrifugation process to concentrate the platelets. The PRP was injected locally into the affected areas. For cervical ectropion and recurrent candidiasis, two doses were administered over one month, while for SUI, three doses were given at monthly intervals. Clinical outcomes were assessed through follow-up exams, symptom relief, and patient-reported improvements. Results: All three patients showed significant clinical improvements following PRP therapy. The patient with cervical ectropion experienced resolution of chronic cervicitis and alleviation of symptoms, while the patient with recurrent candidiasis demonstrated complete symptom resolution without further recurrence. The patient with stress urinary incontinence exhibited a marked improvement in her vaginal health score and a reduction in incontinence episodes. No adverse effects were reported in any case. Conclusion: PRP therapy proved to be an effective, non-invasive treatment option for various gynecological conditions in this case series. It provided significant symptom relief in patients with refractory cervical ectropion, recurrent candidiasis, and stress urinary incontinence. Given its promising results, PRP represents a potential alternative to conventional therapies, particularly in patients who are unresponsive to standard treatments or for whom hormone-based therapies are contraindicated. Further studies are warranted to establish standardized protocols and confirm long-term efficacy.