Azelaic Acid Cream and its Effect on Acne Patients: Evaluation of the Positive and Negative Aspects

Background: The excellent profile of the 20% azelaic acid cream makes it a recommended topical therapy for acne. Objective: This study focused largely on evaluating the outcomes of Azelaic acid cream use on patients with acne and identifying its impact on general health and quality of life. Methodology: We enrolled 82 female patients with acne, aged between 14 and 26 years, between March 2023 and November 2024. All patients underwent several questionnaires to assess skin quality, acne severity, and its impact on patient's quality of life using the Dermatology Life Quality Index (DLQI) and Investigator's Global Assessment (IGA) scales. Findings: Our study were enrolled all outcomes of females with ages 14 - 26 years. Due to that, 54.88% of patients had seborrheic, and 63.41% sited in the face. According to the efficiency of azelaic acid cream use, 46.34% got nearly clear skin, and 19.51% got clear skin among all total patients. Azelaic acid cream showed high improvements of skin in each of acne lesions {67.07%} acne severity {62.20%}, comedones {87.80%}, papules {53.66%}, and pustules {45.12.%}.Conclusion: Adult women's quality of life and acne severity are significantly enhanced using azelaic acid lotion