A Review on Method Development and Validation

Developing analytical methods and then validating them is a crucial step in the drug discovery process. The absence of an approved analytical technique will prevent the medicine from reaching the market, even though it has good potency. As a result, the quality and safety of the medication. In order to assess the stability of the drugs in the presence of excipients and other stress conditions encountered during their shelf life period, this review's primary goal is to provide an overview of the traditional and innovative methods available for the analysis of drugs in their raw material and formulated forms. LC-MS, LC-MS-MS, LC NMR-MS, GC-MS, and LC-MS are some of the hyphenated techniques for drug analysis and impurity profiling that are clarified by the review study.