Can ceftriaxone be diluted with Ringer's lactate?
Ceftriaxone is a bactericidal antibiotic from the third generation of cephalosporins. It works by inhibiting the synthesis of the bacterial cell wall. It is the drug of choice in the treatment of a wide variety of infections caused by both gram-positive and gram-negative bacteria. Its spectrum of activity includes Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Neisseria gonorrhoeae, among others. Similarly, ceftriaxone is effective against certain anaerobic bacteria, making it an option for complicated infections, such as those in the respiratory and urinary tracts, as well as in bacterial meningitis. Its effectiveness against some beta-lactamase-producing bacteria also makes it useful against resistant infections. However, as a drug administered intravenously or intramuscularly, it is essential to follow the recommendations for its preparation and administration to avoid risks associated with its use.
Institutions
- Universidad Nacional de Colombia (CO)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2025-04-04
- DOI
- https://doi.org/10.5281/zenodo.15150552
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00