The Human Gut Microbiome: A Review on Its Role in Health, Disease, and Future Interventions

Numerous physiological systems are regulated, and health is maintained by the billions of bacteriathat make up the human gut microbiota. These microbial populations all impact the creation of vitalmetabolites such as vitamins and short-chain fatty acids, immune system regulation, and digestion. Recentstudies have brought attention to their effects on immune-related illnesses such as diabetes, obesity, andinflammatory bowel diseases, as well as metabolic disorders and mental health. The gut-brain axisemphasises even more how important the microbiome is for mental and emotional health. New treatmentapproaches, such as probiotics, prebiotics, and faecal microbiota transplantation, have become possible asthe complex relationships between the gut microbiota and host systems are better understood. Theimportance of gut microbiota to human health is reviewed in this study, which also looks at potentialpossibilities for microbiome-based therapies.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-02
DOI
https://doi.org/10.5281/zenodo.15577349
Primary Topic
Immune Cell Function and Interaction
Type
article
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article

The Human Gut Microbiome: A Review on Its Role in Health, Disease, and Future Interventions

Zenodo (CERN European Organization for Nuclear Research)
Immune Cell Function and Interaction
article

The Human Gut Microbiome: A Review on Its Role in Health, Disease, and Future Interventions

article en

Abstract

Numerous physiological systems are regulated, and health is maintained by the billions of bacteriathat make up the human gut microbiota. These microbial populations all impact the creation of vitalmetabolites such as vitamins and short-chain fatty acids, immune system regulation, and digestion. Recentstudies have brought attention to their effects on immune-related illnesses such as diabetes, obesity, andinflammatory bowel diseases, as well as metabolic disorders and mental health. The gut-brain axisemphasises even more how important the microbiome is for mental and emotional health. New treatmentapproaches, such as probiotics, prebiotics, and faecal microbiota transplantation, have become possible asthe complex relationships between the gut microbiota and host systems are better understood. Theimportance of gut microbiota to human health is reviewed in this study, which also looks at potentialpossibilities for microbiome-based therapies.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 50%
Immune Cell Function and Interaction
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The Human Gut Microbiome: A Review on Its Role in Health, Disease, and Future Interventions · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS