Preparation And Evaluation Of Herbal Emulgel
The goal of this study is to create and assess an emulgel for the treatment of oral ulcers that contains clove oil, curcumin, and Argemone maxicana latex. Emulgels have emerged as a possibly useful delivery system for hydrophobic drugs. As a penetration booster, menthol was utilised, which also gives ulcers a cooling effect. Clove oil also serves this purpose. Herbal remedies with strong antiulcer properties include menthol, curcumin, and clove oil. While Argemone maxicana exhibits antimicrobial action, clove oil possesses anlgesic and antioxidant properties. While menthol offers cooling properties, curcumin, which is derived from curcuma longa, has anti-inflammatory and antibacterial properties. While menthol soothes mouth sores or ulcers. Diffusion tests, viscosity, spreadability, extrudability, and short-term stability were performed on five formulations. By the conclusion of the following analysis, the optimised formulation revealed that the medicines' respective releases—clove and curcumin—were 79 ± 3.2% and 72.07 ± 4.8%. The results of the investigation indicate that the emulgel has improved penetration properties and can be applied topically.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-10-30
- DOI
- https://doi.org/10.5281/zenodo.14013733
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00