Formulation And Evaluation Of Paracetamol Tablet To Assess

Although oral dose forms have several disadvantages, such as delayed beginning of effect due to sluggish absorption, they are still the most commonly used method of administering medication. Although administering the drug in liquid form helps get around this, many APIs only use a certain amount of consistency in liquid form. Effervescent Tablets therefore serve as a substitute dose form. Just before administration, the tablet is put to a glass of drink, and the pharmaceutical solution or dispersion is meant to be consumed right away. Due to the interaction of tartaric and citric acid with alkali metal carbonates or hydrogen carbonate in the presence of water, the tablet breaks apart quickly through internal CO2 release in water. Because of the CO2 gas released, the API dissolves in water. Addition to taste masking effect is enhanced.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-13
DOI
https://doi.org/10.5281/zenodo.13756038
Primary Topic
Holomorphic and Operator Theory
Type
article
Field-Weighted Citation Impact
0.00
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article

Formulation And Evaluation Of Paracetamol Tablet To Assess

Zenodo (CERN European Organization for Nuclear Research)
Holomorphic and Operator Theory
article

Formulation And Evaluation Of Paracetamol Tablet To Assess

article en

Abstract

Although oral dose forms have several disadvantages, such as delayed beginning of effect due to sluggish absorption, they are still the most commonly used method of administering medication. Although administering the drug in liquid form helps get around this, many APIs only use a certain amount of consistency in liquid form. Effervescent Tablets therefore serve as a substitute dose form. Just before administration, the tablet is put to a glass of drink, and the pharmaceutical solution or dispersion is meant to be consumed right away. Due to the interaction of tartaric and citric acid with alkali metal carbonates or hydrogen carbonate in the presence of water, the tablet breaks apart quickly through internal CO2 release in water. Because of the CO2 gas released, the API dissolves in water. Addition to taste masking effect is enhanced.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 43%
Holomorphic and Operator Theory
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