Mucinous Appendiceal Neoplasm: Minimally Invasive Treatment as a First Step. Case series

Background: Mucinous appendiceal neoplasms (MANs) are rare epithelial tumors, representing <1% of appendectomy specimens. They are often discovered incidentally during surgery for appendicitis or imaging studies, with nonspecific symptoms like abdominal pain and distension. This study presents three cases of mucinous appendiceal neoplasms treated over the last decade with varied presentations, including acute abdomen, chronic diarrhea, and ureterolithiasis. All patients underwent laparoscopic appendectomy as the initial treatment, revealing low-grade mucinous neoplasms with negative margins, and none required further oncological treatment. The diagnosis of MANs relies on imaging techniques such as CT and MRI, along with tumor markers. Surgical resection, preferably appendectomy, is the standard treatment for low-grade lesions confined to the appendix, while more extensive procedures like right hemicolectomy may be indicated for invasive cases. Proper surgical handling is essential to prevent pseudomyxoma peritonei. This series highlights the importance of minimally invasive surgery for initial management and the need for a multidisciplinary approach in these rare tumors. Keywords: Mucinous appendiceal neoplasms.